Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997451 | 0.78 | NOTUM (0.30) | PTGER1 | |
| SCHEMBL23997262 | 0.65 | MAPT (0.43) | — | |
| SCHEMBL23997175 | 0.65 | NTRK1 (0.35) | — | |
| SCHEMBL23997213 | 0.64 | — | — | |
| SCHEMBL23997442 | 0.64 | — | — | |
| SCHEMBL25237152 | 0.64 | RAB9A (0.38) | SLC6A4 | |
| SCHEMBL23997165 | 0.64 | KMT2A (0.41) | — | |
| SCHEMBL23997321 | 0.63 | — | — | |
| SCHEMBL23997412 | 0.62 | L3MBTL1 (0.49) | — | |
| SCHEMBL29274137 | 0.62 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |