Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997348 | 0.78 | PTGER1 (0.31) | PTGER1 | |
| SCHEMBL30578709 | 0.71 | KMT2A (0.44) | NOTUMMAPT | |
| Ethoxycarbonyl Group SCHEMBL29082342 | 0.70 | KMT2A (0.36) | LMNAMAPT | |
| SCHEMBL29291077 | 0.69 | ALOX12 (0.40) | NOTUMPTGER1LMNAMAPT | |
| SCHEMBL23997423 | 0.65 | MAPT (0.35) | NOTUMMAPT | |
| SCHEMBL23997484 | 0.64 | MAPT (0.61) | LMNAMAPT | |
| SCHEMBL2096052 | 0.61 | SIGMAR1 (0.41) | LMNA | |
| SCHEMBL29291073 | 0.61 | LMNA (0.40) | NOTUMPTGER1LMNAMAPT | |
| Ethoxycarbonyl Group SCHEMBL27606185 | 0.61 | NPSR1 (0.38) | NOTUMLMNAMAPT | |
| Ethoxycarbonyl Group SCHEMBL28264125 | 0.60 | SMN1; SMN2 (0.35) | NOTUMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |