Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633866 | 0.90 | THRB (0.57) | THRBTP53MCHR1NPC1RAB9A | |
| SCHEMBL24011432 | 0.84 | MAPT (0.57) | THRBTP53MCHR1NPC1RAB9A | |
| SCHEMBL24011561 | 0.84 | THRB (0.57) | THRBTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011331 | 0.83 | RAB9A (0.57) | THRBTP53MCHR1NPC1RAB9A | |
| SCHEMBL24011484 | 0.83 | RAB9A (0.57) | THRBTP53MCHR1NPC1RAB9A | |
| SCHEMBL24011335 | 0.83 | RAB9A (0.57) | THRBTP53MCHR1NPC1RAB9A | |
| SCHEMBL24011286 | 0.78 | NPC1 (0.53) | THRBTP53MCHR1NPC1RAB9A | |
| SCHEMBL24011431 | 0.77 | RAB9A (0.61) | MCHR1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24011436 | 0.76 | SMN1; SMN2 (0.63) | MCHR1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24011546 | 0.75 | NPC1 (0.68) | MCHR1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | THRB 1014/4885TP53 4796/4885MCHR1 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.