Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011234 | 0.85 | NPC1 (0.54) | HRH1CCR3SIRT5RAB9ANPC1 | |
| SCHEMBL24011682 | 0.78 | PRKAB2 (0.56) | ALDH1A1SMN1; SMN2PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL16000494 | 0.77 | HRH1 (0.51) | HRH1CCR3RAB9APKM | |
| SCHEMBL24011556 | 0.77 | ACHE (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24011319 | 0.77 | POLB (0.43) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16002987 | 0.75 | HRH1 (0.53) | HRH1CCR3RAB9AALDH1A1PKM | |
| SCHEMBL26633674 | 0.74 | SMN1; SMN2 (0.48) | SIRT5RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24011203 | 0.72 | NPC1 (0.60) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24011230 | 0.71 | EPHX2 (0.61) | RAB9ANPC1ALDH1A1LMNATP53 | |
| SCHEMBL24011333 | 0.71 | NPC1 (0.58) | RAB9ANPC1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |