Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012368 | 0.85 | KMT2A (0.45) | KMT2ANCF1HPGDMEN1CA12 | |
| SCHEMBL24012361 | 0.83 | CA12 (0.48) | KMT2ANCF1HPGDMEN1CA12 | |
| SCHEMBL21806210 | 0.80 | MAOB (0.46) | KMT2ANCF1CA12CA1CA2 | |
| SCHEMBL21909542 | 0.79 | MAOB (0.45) | KMT2ACA12CA1CA2CA4 | |
| SCHEMBL21806750 | 0.79 | BCHE (0.43) | KMT2AHPGDMEN1CA12CA1 | |
| SCHEMBL21806190 | 0.77 | MAOB (0.42) | KMT2ACA12CA1CA2CA4 | |
| SCHEMBL21806200 | 0.75 | CA12 (0.43) | KMT2ANCF1CA12CA1CA2 | |
| SCHEMBL24012369 | 0.74 | MAOB (0.45) | KMT2ANCF1HPGDCA12CA1 | |
| SCHEMBL11054587 | 0.72 | KDM4E (0.76) | KMT2AHPGDMEN1CA12CA1 | |
| SCHEMBL22349912 | 0.70 | TSHR (0.56) | KMT2AHPGDMEN1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |