Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012369 | 0.90 | MAOB (0.45) | KMT2AHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL24012357 | 0.85 | KMT2A (0.53) | KMT2AHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL24012367 | 0.80 | MAOB (0.38) | KMT2AHSD17B10KDM4EALDH1A1CA12 | |
| SCHEMBL24012361 | 0.80 | CA12 (0.48) | KMT2AHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL21806248 | 0.78 | CA12 (0.40) | HSD17B10HPGDKDM4EALDH1A1NCF1 | |
| SCHEMBL24012362 | 0.77 | ALDH1A1 (0.35) | KMT2AHSD17B10KDM4EALDH1A1CA12 | |
| SCHEMBL24012355 | 0.74 | HPGD (0.43) | KMT2AHPGDKDM4EALDH1A1GLA | |
| SCHEMBL18885626 | 0.73 | SMN1; SMN2 (0.42) | KMT2AHPGDCA12CA1CA2 | |
| SCHEMBL12690424 | 0.72 | SMN1; SMN2 (0.40) | KMT2AHPGDCA12CA1CA2 | |
| SCHEMBL30837144 | 0.72 | SMN1; SMN2 (0.40) | KMT2AHPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |