Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA5A | P35218 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012357 | 0.83 | KMT2A (0.53) | CA12CA1CA2CA4CA5A | |
| SCHEMBL24012368 | 0.80 | KMT2A (0.45) | CA12CA1CA2CA4CA5A | |
| Trifluoroacetic Acid SCHEMBL21806629 | 0.71 | AKR1B10 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL24012369 | 0.70 | MAOB (0.45) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11054587 | 0.70 | KDM4E (0.76) | CA12CA1CA2CA4CA5A | |
| SCHEMBL25279702 | 0.69 | AKR1B10 (0.75) | CA12CA1CA2CA4CA5A | |
| SCHEMBL25708668 | 0.68 | AKR1B10 (0.77) | CA12CA1CA2CA4CA5A | |
| SCHEMBL21806631 | 0.67 | CA12 (0.47) | CA12CA1CA2CA4CA5A | |
| SCHEMBL25235579 | 0.67 | AKR1B10 (0.64) | CA12CA1CA2CA4CA5A | |
| SCHEMBL21806210 | 0.66 | MAOB (0.46) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |