Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012368 | 0.90 | KMT2A (0.45) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL24012367 | 0.85 | MAOB (0.38) | MAOBALDH1A1KDM4EHSD17B10CA12 | |
| SCHEMBL21806248 | 0.81 | CA12 (0.40) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL24012362 | 0.80 | ALDH1A1 (0.35) | MAOBALDH1A1KDM4EHSD17B10CA12 | |
| SCHEMBL21806658 | 0.78 | MAOB (0.33) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL13248268 | 0.75 | ALDH1A1 (0.51) | MAOBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL24012357 | 0.74 | KMT2A (0.53) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL24012355 | 0.73 | HPGD (0.43) | ALDH1A1HPGDKDM4EGLAKMT2A | |
| SCHEMBL18885626 | 0.71 | SMN1; SMN2 (0.42) | HPGDMAPK1CA12CA1CA2 | |
| SCHEMBL21806210 | 0.71 | MAOB (0.46) | MAOBALDH1A1KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |