SCHEMBL24017113

SCHEMBL24017113

c1ccc2c(c1)CN[C@@H]([C@@H]1NCc3ccccc3-c3ccccc31)c1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.43
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
PNMT P11086 3/20 0.40
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
PRCP P42785 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017135 1.00 HTR2A (0.43) HTR2ACA12CA9PNMTCHRNB2
SCHEMBL1721026 0.71 DRD1 (0.35) PNMTPRCP
SCHEMBL1165406 0.69 CA12 (0.52) CA12CA9PNMTPRCP
SCHEMBL2975011 0.68 CA12 (0.35) CA12CA9PNMTCHRNB2CHRNA4
Hydrochloric Acid SCHEMBL32672905 0.67 CA12 (0.50) CA12CA9PNMTPRCP
SCHEMBL11824601 0.66 OPRM1 (0.44) PNMT
SCHEMBL14395237 0.65 CHRNB2 (0.44) CHRNB2CHRNA4
SCHEMBL359803 0.65 CHRNB2 (0.44) CHRNB2CHRNA4
SCHEMBL2275751 0.65 CYP2D6 (0.41) PNMTCHRNB2CHRNA4PRCP
SCHEMBL6702423 0.65 PNMT (0.42) PNMTCHRNB2CHRNA4PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021223156-A1 DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2021-11-11 WO disclosed