Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014253 | 0.78 | PRCP (0.58) | PRCPMAPTTSHR | |
| SCHEMBL9009806 | 0.74 | HTR2A (0.40) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL6702423 | 0.73 | PNMT (0.42) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL7257552 | 0.73 | CYP2D6 (0.41) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL1567832 | 0.73 | HTR2A (0.46) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL359802 | 0.73 | MAPK1 (0.42) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL1566232 | 0.73 | PNMT (0.42) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL14395237 | 0.73 | CHRNB2 (0.44) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL359803 | 0.73 | CHRNB2 (0.44) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 | |
| SCHEMBL13302986 | 0.73 | ALDH1A1 (0.47) | CYP2D6CYP3A4MEN1KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273078-B2 | Half-phthalocyanine-like chelates and synthesis thereof | THE UNIVERSITY OF AKRON (US) | 2016-03-01 | — | — | US | claimed |
| US-20150203520-A1 | HALF-PHTHALOCYANINE-LIKE CHELATES AND SYNTHESIS THEREOF | THE UNIVERSITY OF AKRON | 2015-07-23 | — | — | US | claimed |
| US-9273078-B2 | Half-phthalocyanine-like chelates and synthesis thereof | THE UNIVERSITY OF AKRON (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150203520-A1 | HALF-PHTHALOCYANINE-LIKE CHELATES AND SYNTHESIS THEREOF | THE UNIVERSITY OF AKRON | 2015-07-23 | — | — | US | disclosed |
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203520-A1 | HALF-PHTHALOCYANINE-LIKE CHELATES AND SYNTHESIS THEREOF | PPOX, FHIT, NISCH | CYP2D6 168/4885CYP3A4 806/4885MEN1 396/4885 |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | FLI1, API5, MAVS | CYP2D6 3617/4885CYP3A4 1269/4885MEN1 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.