Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401914 | 1.00 | C5AR1 (0.38) | C5AR1NPSR1SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL2399698 | 0.90 | RAB9A (0.43) | SMN1; SMN2ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL2399700 | 0.90 | RAB9A (0.43) | SMN1; SMN2ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL12268345 | 0.77 | LMNA (0.32) | NPSR1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL4620452 | 0.77 | ALDH1A1 (0.39) | C5AR1SMN1; SMN2ALDH1A1KMT2ARAB9A | |
| SCHEMBL13609928 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL4544753 | 0.76 | ALDH1A1 (0.39) | NPSR1SMN1; SMN2TDP1ALDH1A1KMT2A | |
| SCHEMBL12268367 | 0.74 | — | — | |
| SCHEMBL13609923 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2TDP1ALDH1A1KMT2ARAB9A | |
| SCHEMBL805450 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2TDP1ALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8025867-B2 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2011-09-27 | — | — | US | disclosed |
| EP-1885730-B1 | SILANE MEROCYANINE SULPHONE DERIVATIVES; PHOTOPROTECTING COMPOSITIONS CONTAINING SAME; USE THEREOF AS UV FILTER | OREAL (FR) | 2009-04-22 | — | — | EP | disclosed |
| US-7510703-B2 | UV-photoprotecting/sunscreen compositions comprising silane/siloxane derivatives of merocyanine sulfones | L'OREAL (FR) | 2009-03-31 | — | — | US | disclosed |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2008-12-11 | — | — | US | disclosed |
| EP-1885730-A1 | SILANE MEROCYANINE SULPHONE DERIVATIVES; PHOTOPROTECTING COMPOSITIONS CONTAINING SAME; USE THEREOF AS UV FILTER | L'OREAL (FR) | 2008-02-13 | — | — | EP | disclosed |
| US-20070224147-A1 | UV-photoprotecting/sunscreen compositions comprising silane/siloxane derivatives of merocyanine sulfones | L'OREAL (FR) | 2007-09-27 | — | — | US | disclosed |
| WO-2006032741-A1 | SILANE MEROCYANINE SULPHONE DERIVATIVES; PHOTOPROTECTING COMPOSITIONS CONTAINING SAME; USE THEREOF AS UV FILTER | L'ORÉAL (FR) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224147-A1 | UV-photoprotecting/sunscreen compositions comprising silane/siloxane derivatives of merocyanine sulfones | ERCC1, ERCC5, CRY1 | C5AR1 4119/4885NPSR1 3128/4885SMN1; SMN2 2736/4885 |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | DDT, DSG1, DSC1 | C5AR1 4561/4885NPSR1 4074/4885SMN1; SMN2 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.