Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24021895 | 0.86 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1PDE4A | |
| SCHEMBL2035452 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL24600957 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL2035453 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL27574575 | 0.81 | BCHE (0.44) | ALDH1A1LMNAALBMAPK1PDE4A | |
| SCHEMBL19003220 | 0.80 | BCHE (0.43) | ALDH1A1LMNAALBMAPK1PDE4A | |
| SCHEMBL15713382 | 0.79 | DNPH1 (0.47) | ALDH1A1LMNAALBMAPK1PDE4D | |
| SCHEMBL23584557 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAALBMAPK1PDE4A | |
| SCHEMBL19003221 | 0.79 | PDE4A (0.43) | ALDH1A1LMNAALBMAPK1PDE4A | |
| SCHEMBL22820040 | 0.78 | CYP2C19 (0.42) | ALDH1A1LMNAALBMAPK1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008403-A1 | CYCLIC DI-NUCLEOTIDES COMPOUNDS FOR THE TREATMENT OF CANCER | Eisai R&D Management Co., Ltd. (JP) | 2022-06-08 | — | — | EP | disclosed |
| EP-3582853-B1 | CYCLIC DI-NUCLEOTIDES COMPOUNDS FOR THE TREATMENT OF CANCER | EISAI R&D MAN CO LTD (JP) | 2021-11-17 | — | — | EP | disclosed |