SCHEMBL24022698

SCHEMBL24022698

CSc1ccc(Sc2nc(SC)nc(SC)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SLC6A4 P31645 5/20 0.39
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39
HSP90AA1 P07900 3/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
MAOA P21397 1/20 0.38
HSP90AB1 P08238 2/20 0.37
NISCH Q9Y2I1 1/20 0.37
ROCK1 Q13464 1/20 0.37
CXCL12 P48061 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24022690 0.85 KDM4E (0.40) KDM4EALDH1A1LMNAMAPTL3MBTL1
SCHEMBL24022696 0.84 KDM4E (0.59) KDM4EALDH1A1LMNAMAPTL3MBTL1
SCHEMBL24348447 0.80 KDM4E (0.37) KDM4EALDH1A1LMNAMAPTL3MBTL1
SCHEMBL26999204 0.79 LMNA (0.44) KDM4EALDH1A1LMNAMAPTL3MBTL1
SCHEMBL10916421 0.77 HSP90AA1 (0.61) KDM4EALDH1A1LMNAMAPTL3MBTL1
SCHEMBL7033576 0.76 ALDH1A1 (0.50) ALDH1A1LMNAL3MBTL1SLC6A4NOS3
SCHEMBL13752159 0.75 NPC1 (0.46) ALDH1A1LMNAMAPTL3MBTL1
SCHEMBL10916129 0.73 LMNA (0.49) KDM4EALDH1A1LMNAMAPTL3MBTL1
SCHEMBL83839 0.72 ALDH1A1 (0.58) ALDH1A1SLC6A4NOS3NOS1SLC6A2
SCHEMBL7537282 0.72 HSP90AB1 (0.48) KDM4EALDH1A1LMNAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872546-B2 Catalyst for hydrogenation reaction and method for producing same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
EP-3909676-A1 CATALYST FOR HYDROGENATION REACTION AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2021-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11872546-B2 Catalyst for hydrogenation reaction and method for producing same GRHPR, HAO2, HACL2 KDM4E 3249/4885ALDH1A1 2211/4885LMNA 4748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.