Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 9/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849593 | 0.98 | SMPD1 (0.40) | SMPD1LMNAGBA1CYP19A1ADA | |
| SCHEMBL24023303 | 0.86 | CYP19A1 (0.36) | SMPD1GBA1CYP19A1 | |
| SCHEMBL23265136 | 0.84 | SMPD1 (0.48) | SMPD1GBA1 | |
| SCHEMBL16921661 | 0.83 | SMPD1 (0.38) | SMPD1GBA1CYP19A1ADA | |
| SCHEMBL24775851 | 0.75 | CYP19A1 (0.38) | CYP19A1 | |
| SCHEMBL24849594 | 0.74 | GABRA2 (0.33) | SMPD1CYP19A1 | |
| SCHEMBL24849931 | 0.72 | CYP19A1 (0.35) | SMPD1GBA1CYP19A1 | |
| SCHEMBL21557588 | 0.71 | — | — | |
| SCHEMBL23957806 | 0.71 | EGLN2 (0.33) | — | |
| SCHEMBL10080835 | 0.68 | SMPD1 (0.50) | SMPD1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174281-B1 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174281-B1 | Modified nucleotides and uses thereof | NUDT1, RNMT, ADAR | SMPD1 1208/4885LMNA 901/4885GBA1 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.