SCHEMBL24026071

SCHEMBL24026071

Fc1ccccc1-c1cc(F)c(Br)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.50
PTPN1 P18031 1/20 0.50
FEN1 P39748 7/20 0.46
ALOX5AP P20292 5/20 0.46
PDK2 Q15119 1/20 0.42
ACMSD Q8TDX5 1/20 0.41
TNKS O95271 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
BACE1 P56817 1/20 0.40
TRPA1 O75762 1/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
DHODH Q02127 1/20 0.39
ERN1 O75460 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAP4K4 O95819 1/20 0.38
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24723508 0.84 ALDH1A1 (0.48) FEN1ALOX5APBACE1ALDH1A1MAPT
SCHEMBL28116695 0.83 PTPRC (0.54) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL20593949 0.82 PTPRC (0.46) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL30665737 0.81 PTPRC (0.48) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL13439489 0.81 PTPRC (0.48) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL13614897 0.79 PTPRC (0.47) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL1772366 0.79 ALDH1A1 (0.50) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL13614398 0.78 PTPRC (0.56) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL1337677 0.77 FEN1 (0.47) PTPRCPTPN1FEN1ALOX5APPDK2
SCHEMBL23989236 0.76 ALDH1A1 (0.52) FEN1ALOX5APCYP11B1CYP11B2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210359222-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210359222-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE RXFP4, RER1, RXFP1 PTPRC 4081/4885PTPN1 2075/4885FEN1 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.