SCHEMBL24028201

SCHEMBL24028201

CS(=O)(=O)NC(=O)C12CC3CC(C1)CC(C(=O)OCC(F)C(F)(F)S(=O)(=O)O)(C3)C2

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 3/20 0.34
ABL1 P00519 1/20 0.34
TSHR P16473 1/20 0.34
RIN1 Q13671 1/20 0.34
PRKCA P17252 1/20 0.34
PKM P14618 2/20 0.33
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SCN9A Q15858 1/20 0.31
THRB P10828 1/20 0.31
HSD11B1 P28845 1/20 0.31
HSD11B2 P80365 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27445713 0.89 NPSR1 (0.39) NPSR1LMNAABL1TSHRRIN1
SCHEMBL18235966 0.82 ALDH1A1 (0.46) NPSR1LMNAABL1TSHRRIN1
SCHEMBL12257077 0.82 PRKCA (0.49) NPSR1LMNAPRKCAPKMALDH1A1
SCHEMBL24028727 0.80 HSD11B1 (0.39) NPSR1LMNAKMT2ASCN9AHSD11B1
SCHEMBL18235965 0.74 ALDH1A1 (0.42) NPSR1LMNATSHRPRKCAPKM
SCHEMBL18232581 0.74 ALDH1A1 (0.45) NPSR1LMNAABL1TSHRRIN1
SCHEMBL26451950 0.74 NPSR1 (0.41) NPSR1LMNAABL1TSHRRIN1
SCHEMBL29870112 0.74 NPSR1 (0.44) NPSR1LMNAABL1TSHRRIN1
SCHEMBL27445084 0.73 NPSR1 (0.40) NPSR1LMNAABL1TSHRRIN1
Hydrogen Sulfide SCHEMBL29869678 0.73 ALDH1A1 (0.44) NPSR1LMNAABL1TSHRRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-20210356862-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210356862-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE RER1, COL1A1, RAD51 NPSR1 2926/4885LMNA 143/4885ABL1 1980/4885
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device RER1, COL1A1, RAD51 NPSR1 2926/4885LMNA 143/4885ABL1 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.