SCHEMBL24028378

SCHEMBL24028378

O=C(NC(=O)C(F)(F)S(=O)(=O)O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
LMNA P02545 3/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HTT P42858 2/20 0.43
POLB P06746 2/20 0.41
P2RX7 Q99572 5/20 0.41
P2RX4 Q99571 3/20 0.41
GAA P10253 1/20 0.41
CNR2 P34972 1/20 0.41
EPHX1 P07099 1/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
GLA P06280 1/20 0.39
ALOX12 P18054 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24028734 0.82 ALDH1A1 (0.41) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL16000784 0.81 ALDH1A1 (0.51) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL27445070 0.81 ALDH1A1 (0.43) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL27444946 0.78 ALDH1A1 (0.58) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL16724520 0.78 ALDH1A1 (0.40) ALDH1A1LMNANPSR1HTTGAA
SCHEMBL10272971 0.77 EPHX2 (0.50) ALDH1A1LMNANPSR1HTTEPHX1
SCHEMBL23808381 0.74 ALDH1A1 (0.41) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL25765152 0.74 ALDH1A1 (0.57) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL24028213 0.74 ALDH1A1 (0.40) ALDH1A1LMNANPSR1HTTPOLB
SCHEMBL27445698 0.74 ALDH1A1 (0.43) ALDH1A1LMNANPSR1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-20210356862-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210356862-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE RER1, COL1A1, RAD51 ALDH1A1 762/4885LMNA 143/4885NPSR1 2926/4885
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device RER1, COL1A1, RAD51 ALDH1A1 762/4885LMNA 143/4885NPSR1 2926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.