Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433073 | 0.86 | TSHR (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL22292462 | 0.82 | LMNA (0.36) | GAAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22500128 | 0.79 | ALDH1A1 (0.47) | ACE2MAPTALDH1A1KMT2A | |
| SCHEMBL11677049 | 0.79 | ALDH1A1 (0.47) | ACE2MAPTALDH1A1KMT2A | |
| SCHEMBL11677487 | 0.79 | ALDH1A1 (0.47) | ACE2MAPTALDH1A1KMT2A | |
| SCHEMBL19038153 | 0.77 | CYP1A2 (0.48) | ACE2MAPTALDH1A1KMT2A | |
| SCHEMBL5809132 | 0.76 | GNAO1 (0.47) | ACE2MAPTPRKD3PRKCGPRKCB | |
| SCHEMBL23332959 | 0.76 | GNAI3 (0.40) | ACE2MAPTALDH1A1KMT2APRKD3 | |
| SCHEMBL21859527 | 0.75 | ACE2 (0.39) | ACE2MAPTLMNAADH1BADH1C | |
| SCHEMBL23128664 | 0.74 | OPRM1 (0.39) | ACE2MAPTALDH1A1KMT2APRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353781-A1 | SURFACE-MODIFIED CELLS, METHODS OF MAKING AND USING | UNITED STATES GOVERNMENT | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353781-A1 | SURFACE-MODIFIED CELLS, METHODS OF MAKING AND USING | CD4, EPCAM, CD2 | ACE2 3689/4885MAPT 2795/4885GAA 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.