Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.51 |
| ▸ | GCK | P35557 | 13/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466459 | 0.88 | DEGS1 (0.44) | GCKRARARARBRARGDEGS1 | |
| SCHEMBL2406820 | 0.81 | NPC1 (0.53) | — | |
| SCHEMBL2405587 | 0.76 | P4HTM (0.50) | — | |
| SCHEMBL2405272 | 0.76 | KMT2A (0.43) | — | |
| SCHEMBL2405376 | 0.76 | NPC1 (0.62) | — | |
| SCHEMBL2404005 | 0.75 | HCAR3 (0.52) | HCAR3GCKRARARARBRARG | |
| SCHEMBL2407431 | 0.72 | THRB (0.55) | — | |
| SCHEMBL2403462 | 0.71 | PTGER4 (0.46) | HCAR2 | |
| SCHEMBL27451977 | 0.71 | HCAR3 (0.69) | HCAR3GCKRARARARBRARG | |
| SCHEMBL2403655 | 0.71 | RNASEH1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2189445-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUND | Research Foundation Itsuu Laboratory (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189445-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUND | Research Foundation Itsuu Laboratory (JP) | 2010-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RXRA, RXRG, RXRB | HCAR3 84/4885GCK 2565/4885RARA 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.