Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 14/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408526 | 0.88 | MEN1 (0.43) | P4HTMMEN1LMNAMAPTKMT2A | |
| SCHEMBL2406820 | 0.81 | NPC1 (0.53) | MEN1LMNAKMT2A | |
| SCHEMBL2406209 | 0.78 | SMN1; SMN2 (0.59) | MEN1KMT2A | |
| SCHEMBL2411251 | 0.77 | RARA (0.46) | MEN1MAPTKMT2A | |
| SCHEMBL2405520 | 0.77 | PKM (0.51) | MAPTKMT2A | |
| SCHEMBL2403471 | 0.76 | HCAR3 (0.51) | — | |
| SCHEMBL2405034 | 0.76 | AKR1C3 (0.44) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL2405272 | 0.76 | KMT2A (0.43) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL2405376 | 0.76 | NPC1 (0.62) | MEN1MAPTKMT2A | |
| SCHEMBL2405602 | 0.75 | MAPT (0.52) | MEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2189445-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUND | Research Foundation Itsuu Laboratory (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189445-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUND | Research Foundation Itsuu Laboratory (JP) | 2010-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RXRA, RXRG, RXRB | P4HTM 2395/4885MEN1 1614/4885LMNA 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.