Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.60 |
| ▸ | CYCS | P99999 | 3/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910535 | 0.95 | ABCG2 (0.55) | TOP1CYCSABCG2ENPP2SMN1; SMN2 | |
| SCHEMBL14077524 | 0.93 | ABCG2 (0.54) | TOP1CYCSABCG2ENPP2SMN1; SMN2 | |
| SCHEMBL7241022 | 0.93 | TOP1 (0.58) | TOP1CYCSABCG2ENPP2SMN1; SMN2 | |
| SCHEMBL7265156 | 0.88 | MTNR1A (0.53) | TOP1CYCSABCG2ENPP2SMN1; SMN2 | |
| SCHEMBL7239829 | 0.88 | ALDH1A1 (0.54) | TOP1CYCSABCG2ENPP2SMN1; SMN2 | |
| SCHEMBL1974241 | 0.88 | TOP1 (0.68) | TOP1CYCSABCG2ENPP2SMN1; SMN2 | |
| SCHEMBL22461493 | 0.85 | TERT (0.58) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL22461492 | 0.85 | TERT (0.58) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL22461491 | 0.85 | TERT (0.58) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL7241342 | 0.84 | TOP1 (0.44) | TOP1CYCSABCG2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501515-B1 | Optical recording material | TORAY INDUSTRIES (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5306599-A | Optical recording material | TORAY INDUSTRIES, INC. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0501515-A1 | Optical recording material | TORAY INDUSTRIES, INC. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4837221-A | ADMINISTERING PORPHYRIN DERIVATIVE TO LOCATE TUMOR, ILLUMINATING WITH LIGHT | EFAMOL LTD. (GB) | 1989-06-06 | — | — | US | disclosed |
| EP-0186962-A1 | Porphyrins and cancer treatment | EFAMOL LIMITED (GB) | 1986-07-09 | — | — | EP | disclosed |