Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 5/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | SLC8A1 | P32418 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29834721 | 0.81 | ABCB1 (0.43) | KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23355309 | 0.76 | RAB9A (0.51) | KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23368138 | 0.70 | HSD17B10 (0.47) | KDM4EALDH1A1GCKSMN1; SMN2 | |
| SCHEMBL21612796 | 0.69 | SHMT1 (0.40) | KDM4EALDH1A1GCKSMN1; SMN2 | |
| SCHEMBL24037369 | 0.69 | ALDH1A1 (0.34) | ALDH1A1GCK | |
| Hydrochloric Acid SCHEMBL30203152 | 0.69 | HSD17B10 (0.46) | KDM4EALDH1A1GCKSMN1; SMN2 | |
| SCHEMBL24037618 | 0.67 | PIM1 (0.32) | ALDH1A1 | |
| SCHEMBL29834712 | 0.67 | KDR (0.41) | ALDH1A1SLC8A1SMN1; SMN2 | |
| SCHEMBL23355313 | 0.67 | GCK (0.36) | KDM4EALDH1A1GCKSMN1; SMN2 | |
| SCHEMBL23355335 | 0.67 | LMNA (0.41) | SLC8A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231400-A1 | BIS-ARYL ETHERS CONTAINING N-ACYL AZETIDINE AS EGFR/HER2 INHIBITORS | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2021-11-18 | — | — | WO | disclosed |