Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | GHSR | Q92847 | 13/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30920109 | 0.92 | GHSR (0.45) | GPR119GHSR | |
| SCHEMBL24031466 | 0.92 | GHSR (0.45) | GPR119GHSR | |
| SCHEMBL24038710 | 0.89 | GHSR (0.46) | RORCGPR119GHSRCYP2D6KCNH2 | |
| SCHEMBL24031031 | 0.88 | GPR119 (0.49) | RORCGPR119GHSR | |
| SCHEMBL24038697 | 0.87 | GHSR (0.46) | GPR119GHSR | |
| SCHEMBL25895663 | 0.82 | GHSR (0.46) | GHSR | |
| SCHEMBL17391030 | 0.82 | GHSR (0.54) | GHSR | |
| SCHEMBL17391103 | 0.82 | GHSR (0.57) | GHSR | |
| SCHEMBL2081445 | 0.81 | ESR2 (0.49) | GHSR | |
| SCHEMBL24031477 | 0.81 | GHSR (0.49) | GPR119GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580188-A | Can be used as ROR gamma regulator aniline compound (B) | 励缔(杭州)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-113773251-B | Anilines useful as rory modulators | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| US-20230192620-A1 | ANILINE COMPOUND USED AS RORy REGULATOR | SHANGHAI LITEDD CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192620-A1 | ANILINE COMPOUND USED AS RORy REGULATOR | SHANGHAI LITEDD CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| CN-113773251-A | Anilines useful as ROR gamma modulators | 上海辉启生物医药科技有限公司 | 2021-12-10 | — | — | CN | disclosed |
| WO-2021228217-A1 | ANILINE COMPOUND USED AS RORγ REGULATOR | 上海辉启生物医药科技有限公司 | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192620-A1 | ANILINE COMPOUND USED AS RORy REGULATOR | RORB, RORA, RORC | RORC 3/4885GPR119 240/4885GHSR 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.