Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MYOC | Q99972 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211198 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL4367409 | 0.93 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL3317059 | 0.93 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL240405 | 0.93 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL27546222 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL4371678 | 0.92 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL1230535 | 0.92 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL240404 | 0.92 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL13902136 | 0.84 | RAB9A (0.59) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL6921335 | 0.82 | GAA (0.57) | ALDH1A1KMT2AMAPTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-03-26 | — | — | US | disclosed |
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |
| EP-1883629-A2 | NOVEL HETEROCYCLIC DERIVATIVES | Orchid Research Laboratories Limited (IN) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006123229-A2 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | CYP3A5, CYP3A7, UGT2B7 | ALDH1A1 281/4885KMT2A 4164/4885MEN1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.