Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041864 | 0.95 | HTT (0.53) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24041810 | 0.87 | PRPS1 (0.39) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24054701 | 0.83 | KDM4C (0.39) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24041816 | 0.82 | PRPS1 (0.42) | HTTLMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL24041743 | 0.80 | HTT (0.76) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24041804 | 0.78 | HTT (0.63) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24041863 | 0.77 | HTT (0.62) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24041777 | 0.77 | HTT (0.62) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL24041750 | 0.76 | L3MBTL1 (0.74) | LTA4HHTTSMN1; SMN2LMNATSHR | |
| SCHEMBL29832042 | 0.76 | TGFBR1 (0.56) | HTTSMN1; SMN2LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116876-A1 | SOCE Inhibitors and Therapeutic Uses Thereof | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-04-11 | — | — | US | disclosed |
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116876-A1 | SOCE Inhibitors and Therapeutic Uses Thereof | STIM1, ORAI1, STIM2 | LTA4H 853/4885HTT 3725/4885SMN1; SMN2 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.