Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045795 | 0.82 | MKNK1 (0.44) | — | |
| SCHEMBL24045705 | 0.79 | BCHE (0.38) | FAAHPDE3BPDE3AMTOR | |
| SCHEMBL24045718 | 0.78 | BRD4 (0.46) | GRM2BACE1ROCK2 | |
| SCHEMBL24045873 | 0.76 | BACE1 (0.43) | GRM5GRM1BACE1ROCK2 | |
| SCHEMBL24045911 | 0.75 | NAAA (0.40) | FEN1 | |
| SCHEMBL24045788 | 0.75 | BRD9 (0.42) | ROCK2 | |
| SCHEMBL1360514 | 0.74 | MGLL (0.51) | — | |
| SCHEMBL24045740 | 0.73 | GPR119 (0.40) | GRM5ROCK2 | |
| SCHEMBL24045906 | 0.72 | ROCK2 (0.38) | ROCK2 | |
| SCHEMBL24045762 | 0.71 | EGLN1 (0.38) | GRM2FAAHBACE1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |