Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045762 | 0.84 | EGLN1 (0.38) | AURKATTKAURKBINCENPEGLN1 | |
| SCHEMBL24045932 | 0.84 | APP (0.47) | CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL24045773 | 0.79 | CHRNA7 (0.41) | PDE3BPDE3AMTORFAAH | |
| SCHEMBL15875300 | 0.76 | FAAH (0.47) | LMNAFAAHMGLLMEN1ALDH1A1 | |
| SCHEMBL24045716 | 0.76 | FAAH (0.47) | FAAHMGLLMEN1HPGDKMT2A | |
| SCHEMBL24045892 | 0.75 | TAAR1 (0.45) | FAAHMGLLCYP3A4USP2CYP2D6 | |
| SCHEMBL24045795 | 0.75 | MKNK1 (0.44) | PIK3CASMN1; SMN2HTT | |
| SCHEMBL24045791 | 0.75 | CYP11B2 (0.38) | MAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL23168409 | 0.75 | ALDH1A1 (0.53) | LMNAMAPTSMN1; SMN2USP2KDM4E | |
| SCHEMBL24045949 | 0.74 | FPR1 (0.40) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |