Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.35 |
| ▸ | FEN1 | P39748 | 6/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045702 | 0.80 | DGAT1 (0.44) | CYP11B1CYP11B2GRM2MCHR1L3MBTL1 | |
| SCHEMBL24045701 | 0.79 | KDM1A (0.50) | ALOX5APFEN1 | |
| SCHEMBL24045721 | 0.75 | CNR2 (0.43) | CYP11B1CYP11B2ALOX5APFEN1DGAT1 | |
| SCHEMBL24045883 | 0.73 | FPR2 (0.40) | DGAT1 | |
| SCHEMBL24045791 | 0.71 | CYP11B2 (0.38) | NPC1CYP11B1CYP11B2DGAT1 | |
| SCHEMBL24045881 | 0.69 | PTPRC (0.42) | CYP11B1CYP11B2ALOX5APFEN1 | |
| SCHEMBL24045707 | 0.67 | DGAT1 (0.44) | NPC1MCHR1DGAT1 | |
| SCHEMBL24045898 | 0.67 | SLC6A7 (0.40) | MCHR1 | |
| SCHEMBL24045767 | 0.67 | FPR2 (0.42) | L3MBTL1 | |
| SCHEMBL14266793 | 0.66 | MAPT (0.37) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |