Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236766 | 0.83 | LIPG (0.49) | F10LMNAUSP2HPGDTSHR | |
| SCHEMBL24045797 | 0.79 | PRMT6 (0.34) | F10 | |
| SCHEMBL24045796 | 0.78 | F10 (0.47) | F10LMNAHPGDTSHRPRSS1 | |
| SCHEMBL23602041 | 0.76 | F10 (0.52) | F10LMNAHPGDTSHRPRSS1 | |
| SCHEMBL14320491 | 0.75 | F10 (0.50) | F10LMNAHPGDPRSS1PRSS2 | |
| SCHEMBL24045872 | 0.74 | PRMT6 (0.34) | — | |
| SCHEMBL24721515 | 0.74 | BCL2 (0.49) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL24045715 | 0.73 | F10 (0.47) | F10HPGDPRSS1PRSS2PRSS3 | |
| SCHEMBL23601598 | 0.72 | ALDH1A1 (0.49) | F10LMNAHPGDTSHRMAPT | |
| SCHEMBL22236767 | 0.70 | AURKB (0.43) | F10LMNAUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |