Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 7/20 | 0.57 |
| ▸ | GABRD | O14764 | 7/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.57 |
| ▸ | GABRE | P78334 | 7/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568538 | 0.84 | CYP3A4 (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13479744 | 0.80 | CSNK2A2 (0.64) | CSNK2A2CSNK2BCSNK2A1TP53CYP3A4 | |
| SCHEMBL20664412 | 0.74 | ADORA3 (0.76) | CSNK2A2CSNK2BCSNK2A1TP53CYP3A4 | |
| SCHEMBL8532 | 0.73 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9328540 | 0.72 | CYP1A1 (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9138573 | 0.72 | CYP3A4 (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13598259 | 0.72 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1TP53CYP3A4 | |
| SCHEMBL31303695 | 0.72 | CYP3A4 (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28568624 | 0.72 | AHR (0.52) | CSNK2A2CSNK2BCSNK2A1TP53CYP3A4 | |
| SCHEMBL25449242 | 0.71 | AR (0.73) | CSNK2A2CSNK2BCSNK2A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939917-B | Preparation method of flavonoid compound | 中山大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-112939917-A | Preparation method of flavonoid compound | 中山大学 | 2021-06-11 | — | — | CN | disclosed |