Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223854 | 0.83 | ALDH1A1 (0.47) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL24046766 | 0.81 | FDPS (0.42) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29652045 | 0.76 | FDPS (0.71) | KDM4EKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL1396839 | 0.76 | FDPS (0.71) | KDM4EKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL30389775 | 0.76 | TRPC6 (0.44) | FDPSPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21750003 | 0.76 | LMNA (0.45) | KDM4EALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL29861038 | 0.76 | LMNA (0.45) | KDM4EALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL20529099 | 0.75 | SMN1; SMN2 (0.51) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4144977 | 0.73 | FDPS (0.41) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4152949 | 0.73 | FDPS (0.40) | KDM4EKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |