Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750003 | 1.00 | LMNA (0.45) | LMNATSHRPDE4DKDM4EGAA | |
| SCHEMBL1223854 | 0.87 | ALDH1A1 (0.47) | LMNATSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL21761474 | 0.83 | GAA (0.41) | LMNATSHRPDE4DKDM4EGAA | |
| SCHEMBL4144977 | 0.81 | FDPS (0.41) | TSHRKDM4EMAPTALDH1A1FDPS | |
| SCHEMBL23963014 | 0.80 | AMY1A (0.42) | TSHRPDE4DKDM4EGAAMAPT | |
| SCHEMBL24509891 | 0.79 | LMNA (0.41) | LMNATSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL21749950 | 0.79 | ALDH1A1 (0.47) | TSHRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL21749951 | 0.79 | ALDH1A1 (0.47) | TSHRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL21750017 | 0.79 | NFE2L2 (0.38) | LMNATSHRPDE4DKDM4EGAA | |
| SCHEMBL21750019 | 0.79 | NFE2L2 (0.38) | LMNATSHRPDE4DKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291065-B | Novel isoindoline derivative, pharmaceutical composition and application thereof | 康朴生物医药技术（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |