SCHEMBL240470

SCHEMBL240470

Oc1ccccc1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 5/20 0.76
SLC6A2 P23975 3/20 0.76
SLC6A3 Q01959 3/20 0.76
MAPT P10636 3/20 0.76
LMNA P02545 2/20 0.76
NR1I2 O75469 1/20 0.76
PGR P06401 1/20 0.76
HSP90AA1 P07900 1/20 0.76
ADORA3 P0DMS8 1/20 0.76
HSPA5 P11021 1/20 0.76
HPGD P15428 1/20 0.76
CBR1 P16152 1/20 0.76
TBXA2R P21731 1/20 0.76
AGTR1 P30556 1/20 0.76
CHRM1 P11229 1/20 0.56
STK39 Q9UEW8 1/20 0.56
SLC6A4 P31645 2/20 0.54
PLA2G1B P04054 1/20 0.54
ATG4B Q9Y4P1 1/20 0.54
RHEB Q15382 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triclosan SCHEMBL11658912 0.89 TTR (0.71) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL29354475 0.86 TTR (1.00) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL3269 0.86 TTR (1.00) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL526378 0.86 TTR (1.00) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL29356111 0.86 TTR (1.00) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL29367506 0.86 TTR (1.00) TTRSLC6A2SLC6A3MAPTLMNA
SCHEMBL10765474 0.85 TTR (0.76) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL8975439 0.85 TTR (0.96) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL8055151 0.85 TTR (0.96) TTRSLC6A2SLC6A3MAPTLMNA
Triclosan SCHEMBL3895700 0.85 TTR (0.96) TTRSLC6A2SLC6A3MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10555878-B2 Solid antiperspirant and/or deodorant composition in the form of a water-in-oil emulsion based on silicone emulsifiers and on waxes; method for treating body odours L'OREAL (FR) 2020-02-11 US claimed
WO-2018141783-A1 CATHETER HUB MADE OF PLASTIC THAT CONTAINS MOLECULARLY DISPERSED POLYCHLORINATED PHENOXYPHENOL (PCPP) SCHIERHOLZ JOERG MICHAEL (DE) 2018-08-09 WO claimed
WO-2018122014-A1 SUPERHYDROPHOBIC COSMETIC COMPOSITION IN AEROSOL FORM L'OREAL (FR) 2018-07-05 WO claimed
US-20140193471-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'OREAL (FR) 2014-07-10 US claimed
US-20110212144-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'OREAL (FR) 2011-09-01 US claimed
EP-1586304-B2 Water in oil emulsion type deodorant cosmetic composition containing a polyolelfin derivative comprising at least one polar part as emulsifier OREAL (FR) 2011-08-17 EP claimed
US-20110046262-A1 Pasty Insert Material for Widening of Gingival Sulcus and Use Thereof KETTENBACH GMBH & CO. KG (DE) 2011-02-24 US claimed
EP-2229135-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'Oréal (FR) 2010-09-22 EP claimed
WO-2009077453-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'OREAL (FR) 2009-06-25 WO claimed
EP-1550435-B1 Deodorizing oil-in-water emulsion comprising a mixture of alkylpolyglycoside and fatty alcohol and a non ionic associative polyether polyurethane OREAL (FR) 2008-10-22 EP claimed
WO-2003002081-A1 COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002078-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002080-A1 COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002079-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 WO claimed
US-6491899-B1 DENTIFRICES CONTAINING A RETINOL, PANTHENOL AND BACTERICIDES USED AS PROPHYLACTIC AGENTS FOR ORAL DISEASES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-12-10 US claimed
EP-0880892-A1 Controlled release compositions ROHM AND HAAS COMPANY (US) 1998-12-02 EP claimed
EP-0220890-B1 ORAL HYGIENE COMPOSITION BEECHAM GROUP PLC (GB) 1991-09-11 EP claimed
US-5032385-A Dfiphenyl ethers, polyoxyethylene glycol BEECHAM GROUP PLC (GB) 1991-07-16 US claimed
EP-0220890-A2 Oral hygiene composition BEECHAM GROUP PLC (GB) 1987-05-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140193471-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS DGAT1, DGAT2, DDT TTR 2213/4885SLC6A2 899/4885SLC6A3 260/4885
US-20110212144-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS DGAT1, DGAT2, DDT TTR 2213/4885SLC6A2 899/4885SLC6A3 260/4885
US-10555878-B2 Solid antiperspirant and/or deodorant composition in the form of a water-in-oil emulsion based on silicone emulsifiers and on waxes; method for treating body odours DGAT1, DGAT2, DDT TTR 2213/4885SLC6A2 899/4885SLC6A3 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.