Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 4/20 | 0.36 |
| ▸ | CDC25C | P30307 | 4/20 | 0.36 |
| ▸ | ARSA | P15289 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477087 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL25239102 | 0.91 | LMNA (0.41) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL24049724 | 0.78 | ABCG2 (0.36) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL28928983 | 0.75 | HDAC4 (0.41) | ALDH1A1MEN1KMT2AMAPK1CYP1A2 | |
| SCHEMBL25742897 | 0.73 | ABCG2 (0.33) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL28929254 | 0.72 | ADORA3 (0.44) | ALDH1A1HPGDMEN1KMT2ATP53 | |
| SCHEMBL5033199 | 0.72 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL295788 | 0.71 | LMNA (0.37) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL24049749 | 0.70 | CYP11B1 (0.40) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL30477088 | 0.70 | CYP11B1 (0.40) | ALDH1A1LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685743-B2 | Open-shell pi-conjugated molecules exhibiting multidimensional intermolecular covalency, compositions and process for preparing | LEHIGH UNIVERSITY | 2023-06-27 | — | — | US | disclosed |
| US-11685743-B2 | Open-shell pi-conjugated molecules exhibiting multidimensional intermolecular covalency, compositions and process for preparing | LEHIGH UNIVERSITY | 2023-06-27 | — | — | US | disclosed |
| US-20210363153-A1 | OPEN-SHELL PI-CONJUGATED MOLECULES EXHIBITING MULTIDIMENSIONAL INTERMOLECULAR COVALENCY, COMPOSITIONS AND PROCESS FOR PREPARING | LEHIGH UNIVERSITY | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685743-B2 | Open-shell pi-conjugated molecules exhibiting multidimensional intermolecular covalency, compositions and process for preparing | INTS6, INTS9, NCLN | ALDH1A1 4345/4885LMNA 2131/4885HPGD 3662/4885 |
| US-20210363153-A1 | OPEN-SHELL PI-CONJUGATED MOLECULES EXHIBITING MULTIDIMENSIONAL INTERMOLECULAR COVALENCY, COMPOSITIONS AND PROCESS FOR PREPARING | INTS6, INTS9, NCLN | ALDH1A1 4345/4885LMNA 2131/4885HPGD 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.