Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414563 | 0.79 | TSHR (0.55) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10587782 | 0.79 | TSHR (0.50) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10517046 | 0.78 | TSHR (0.63) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19346894 | 0.78 | L3MBTL1 (0.56) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7882975 | 0.78 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7203018 | 0.78 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11762210 | 0.78 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15304002 | 0.77 | ALDH1A1 (0.59) | TSHRL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL11088941 | 0.76 | ALDH1A1 (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6425252 | 0.76 | TSHR (0.61) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393781-A | Water-based bead blasting wall material for cigarettes and preparation method thereof | 武汉市昱宸峰科技有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-111393781-A | Water-based bead blasting wall material for cigarettes and preparation method thereof | 武汉市昱宸峰科技有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-102791365-B | Polyamide membrane with a coating comprising polyalkylene oxide and acetophenone compounds | DOW GLOBAL TECHNOLOGIES LLC | 2014-12-24 | — | — | CN | disclosed |
| US-8721942-B2 | Composite membrane including coating of polyalkylene oxide and acetophenone compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-05-13 | — | — | US | disclosed |
| CN-102791365-A | Polyamide membrane with a coating comprising polyalkylene oxide and acetophenone compounds | DOW GLOBAL TECHNOLOGIES LLC | 2012-11-21 | — | — | CN | disclosed |
| WO-2011112351-A1 | POLYAMIDE MEMBRANE WITH A COATING COMPRISING POLYALKYLENE OXIDE AND ACETOPHENONE COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-15 | — | — | WO | disclosed |
| US-20110220569-A1 | COMPOSITE MEMBRANE INCLUDING COATING OF POLYALKYLENE OXIDE AND ACETOPHENONE COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC | 2011-09-15 | — | — | US | disclosed |
| US-20080027075-A1 | Quaternary Amino-Function Chalcones | LICA PHARMACEUTICALS A/S (DK) | 2008-01-31 | — | — | US | disclosed |
| EP-1682486-A1 | QUATERNARY AMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2006-07-26 | — | — | EP | disclosed |
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | disclosed |
| WO-2005042467-A1 | QUATERNARY AMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2005-05-12 | — | — | WO | disclosed |
| EP-1506157-A2 | AMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097575-A2 | AMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027075-A1 | Quaternary Amino-Function Chalcones | NR2E1, BET1, NR0B1 | TSHR 2635/4885L3MBTL1 2008/4885MAPT 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.