Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13280819 | 0.79 | MAOA (0.41) | L3MBTL1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1414563 | 0.79 | TSHR (0.55) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL633284 | 0.78 | TSHR (0.63) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19346894 | 0.78 | L3MBTL1 (0.56) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11762210 | 0.78 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2405059 | 0.78 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7882975 | 0.78 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11088941 | 0.76 | ALDH1A1 (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10587782 | 0.75 | TSHR (0.50) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5158714 | 0.75 | TSHR (0.59) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110939-B1 | Process for the preparation of poly(fluoroalkyl)-acetophenones | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| US-6410796-B2 | PREPARING A DIAZONIUM SALT MIXTURE FROM THE FLUOROALKYL ANILINE COMPOUND, REACTING DIAZONIUM SALT MIXTURE WITH ACETALDOXIME IN PRESENCE OF HALIDE IONS, ATLEAST OTHER STRONG ACID, AND A COPPER AND/OR PALLADIUM COMPOUND, FREE OF BUFFER | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| US-6410796-B2 | PREPARING A DIAZONIUM SALT MIXTURE FROM THE FLUOROALKYL ANILINE COMPOUND, REACTING DIAZONIUM SALT MIXTURE WITH ACETALDOXIME IN PRESENCE OF HALIDE IONS, ATLEAST OTHER STRONG ACID, AND A COPPER AND/OR PALLADIUM COMPOUND, FREE OF BUFFER | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-1110939-A3 | Process for the preparation of poly(fluoroalkyl)-acetophenones | BAYER AG (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-20010005767-A1 | Process for the preparation of poly(fluoroalkyl)acetophenones | LANXESS DEUTSCHLAND GMBH (DE) | 2001-06-28 | — | — | US | disclosed |
| US-20010005767-A1 | Process for the preparation of poly(fluoroalkyl)acetophenones | LANXESS DEUTSCHLAND GMBH (DE) | 2001-06-28 | — | — | US | disclosed |
| EP-1110939-A2 | Process for the preparation of poly(fluoroalkyl)-acetophenones | BAYER AG (DE) | 2001-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010005767-A1 | Process for the preparation of poly(fluoroalkyl)acetophenones | DDT, DDC, AGPS | TSHR 3741/4885L3MBTL1 4563/4885MAPT 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.