Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 9/20 | 0.45 |
| ▸ | ACHE | P22303 | 9/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405195 | 0.84 | HTR2A (0.47) | HTR2AALDH1A1HPGDBCHEACHE | |
| SCHEMBL2406529 | 0.83 | MPO (0.50) | CCR5 | |
| SCHEMBL7867310 | 0.79 | MTNR1A (0.66) | HTR6MTNR1AMTNR1BHTR2AKDM4E | |
| SCHEMBL21808835 | 0.79 | MTNR1A (0.62) | HTR6MTNR1AMTNR1BHTR2AKDM4E | |
| SCHEMBL30708156 | 0.79 | MTNR1A (0.62) | HTR6MTNR1AMTNR1BHTR2AKDM4E | |
| SCHEMBL2404021 | 0.79 | SIGMAR1 (0.62) | HPGDSIGMAR1CCR5 | |
| SCHEMBL1969126 | 0.77 | HTR6 (0.72) | HTR6MTNR1AMTNR1BHTR2ABCHE | |
| SCHEMBL21808890 | 0.77 | PKM (0.61) | HTR6MTNR1AMTNR1BHTR2AKDM4E | |
| SCHEMBL25139456 | 0.76 | MTNR1A (0.60) | HTR6MTNR1AMTNR1BHTR2AKDM4E | |
| SCHEMBL25139803 | 0.76 | MTNR1A (0.60) | HTR6MTNR1AMTNR1BHTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | HTR6 177/4885MTNR1A 23/4885MTNR1B 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.