Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL7867594 | 0.92 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Hydrogen Sulfide SCHEMBL10627246 | 0.92 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Hydrogen Sulfide SCHEMBL28188397 | 0.92 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Benzene SCHEMBL28307046 | 0.92 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Methyl Alcohol SCHEMBL2996522 | 0.90 | TSHR (0.89) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Ethane SCHEMBL4196548 | 0.90 | TSHR (0.89) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Benzene SCHEMBL9751882 | 0.89 | TSHR (1.00) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| SCHEMBL30812783 | 0.89 | TSHR (1.00) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| SCHEMBL597672 | 0.89 | TSHR (1.00) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| SCHEMBL2509 | 0.89 | TSHR (1.00) | TSHRSMN1; SMN2CYP2D6POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051666-B1 | SOLUTION OF TETRAMETHYL AMMONIUM HYDROXIDE IN WATER, PROCESS FOR PREPARING THE SOLUTION AND USE THEREOF | INFINEON TECHNOLOGIES AG (DE) | 2003-04-09 | — | — | EP | claimed |
| US-6472130-B1 | Solution of tetramethylammonium hydroxide in water and a process for preparing the solution | INFINEON TECHNOLOGIES AG (DE) | 2002-10-29 | — | — | US | claimed |
| CN-112513016-B | Sulfur-containing polymerizable monomer and use thereof | 尚美德齿科材料有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-112940432-B | Polymerizable monomer for dental material, composition, adhesive dental material, and kit | 三井化学株式会社 | 2022-12-30 | — | — | CN | disclosed |
| US-20220135512-A1 | LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF | ANGUS CHEMICAL COMPANY (US) | 2022-05-05 | — | — | US | disclosed |
| EP-3956291-A1 | LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF | ANGUS Chemical Company (US) | 2022-02-23 | — | — | EP | disclosed |
| CN-113710644-A | Low toxicity organic tertiary and quaternary amines and uses thereof | 安格斯化学公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-107427414-B | Polymerizable monomer for dental material, composition, adhesive dental material, and kit | 三井化学株式会社 | 2021-07-02 | — | — | CN | disclosed |
| CN-112940432-A | Polymerizable monomer for dental material, composition, adhesive dental material, and kit | 三井化学株式会社 | 2021-06-11 | — | — | CN | disclosed |
| CN-112513016-A | Sulfur-containing polymerizable monomer and use thereof | 尚美德齿科材料有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020214692-A1 | LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF | ANGUS CHEMICAL COMPANY (US) | 2020-10-22 | — | — | WO | disclosed |
| US-6346569-B1 | DISPERSING FEED POLYSUCCINIMIDE WITH DISPERSANT, REACTING DISPERSED POLYSUCCINIMIDE WITH CROSS-LINKING AGENT | MITSUI CHEMICALS, INC. (JP) | 2002-02-12 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |
| US-6103827-A | A TRANSPARENT THERMOPLASTIC RESIN BLENDS | GENERAL ELECTRIC COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-6072024-A | Production process of cross-linked polyaspartic acid resin | MITSUI CHEMICALS, INC. (JP) | 2000-06-06 | — | — | US | disclosed |
| US-5883194-A | RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS | GENERAL ELECTRIC COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| CN-1198444-A | Method for producing crosslinked polyaspartic acid resin | MITSUI CHEMICALS INC (JP) | 1998-11-11 | — | — | CN | disclosed |
| EP-0866084-A2 | Production process of cross-linked polyaspartic acid resin | Mitsui Chemicals, Inc. (JP) | 1998-09-23 | — | — | EP | disclosed |
| CN-1141935-A | Thermoplastic resin composition | GEN ELECTRICS CORP (US) | 1997-02-05 | — | — | CN | disclosed |
| EP-0736574-A2 | Thermoplastic resin composition comprising carbonate and acrylic resin | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135512-A1 | LOW TOXICITY ORGANIC TERTIARY AND QUATERNARY AMINES AND USES THEREOF | TET2, TET1, SAT1 | TSHR 1108/4885SMN1; SMN2 1347/4885CYP2D6 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.