Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293509 | 0.97 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ethane SCHEMBL4196548 | 0.94 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30812783 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30671620 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL1079321 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Benzene SCHEMBL9751882 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL3409457 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL597672 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL2509 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30307036 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045974-B | A kind of bepotastine besilate at salt method | 杭州和泽医药科技有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-103572503-A | Hydrophobic type glass wool blanket and adhesive proportion thereof | CHEN ZHAOFENG | 2014-02-12 | — | — | CN | claimed |
| CN-102618197-A | High-glue content adhesive for flexible glass fiber felt | JIEMING ZHOU | 2012-08-01 | — | — | CN | claimed |
| CN-100540588-C | The preparation method of high-purity nano-sheet polyaniline | UNIV TIANJIN (CN) | 2009-09-16 | — | — | CN | claimed |
| CN-101139440-A | Method for preparing high-purity nano-sheet polyaniline | UNIV TIANJIN (CN) | 2008-03-12 | — | — | CN | claimed |
| WO-2024083204-A1 | SALT AND CRYSTAL FORM OF HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-04-25 | — | — | WO | disclosed |
| CN-115340529-A | Acid addition salt of ROCK inhibitor, crystal form of salt, composition and pharmaceutical application | 武汉朗来科技发展有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114478586-A | Salt or crystal form of inhibitor containing bicyclic derivatives, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113717194-A | Salts of heteroaromatic derivatives and process for preparing the same | 上海翰森生物医药科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113248645-B | Low-melting point polyvinyl alcohol and preparation method thereof | 天津辛德玛悬浮剂有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113493440-A | Salt of nitrogen-containing heteroaromatic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-113248645-A | Low-melting point polyvinyl alcohol and preparation method thereof | 天津辛德玛悬浮剂有限公司 | 2021-08-13 | — | — | CN | disclosed |
| WO-2008155752-A1 | (1R,1'R)-ATRACURIUM SALTS SEPARATION PROCESS | CHEMAGIS LTD. (IL) | 2008-12-24 | — | — | WO | disclosed |
| CN-101287719-A | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment | GALANTOS PHARMA GMBH (DE) | 2008-10-15 | — | — | CN | disclosed |
| CN-101139440-A | Method for preparing high-purity nano-sheet polyaniline | UNIV TIANJIN (CN) | 2008-03-12 | — | — | CN | disclosed |
| US-20070244058-A1 | Galactose Derivative, Drug Carrier and Medicinal Composition | NIPPON SHINYAKU CO., LTD. (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-1783137-A1 | GALACTOSE DERIVATIVE, DRUG CARRIER AND MEDICINAL COMPOSITION | Nippon Shinyaku Co., Ltd. (JP) | 2007-05-09 | — | — | EP | disclosed |
| CN-1269823-C | 3, 7-diazabicyclo [3.3.1] formulations as antiarrhythmic compounds | ASTRAZENECA AB (SE) | 2006-08-16 | — | — | CN | disclosed |
| CN-1514837-A | 3,7-diazabicyclo [3.3.1] for mulations as anti arhythmiccompounds | — | 2004-07-21 | — | — | CN | disclosed |
| US-5635707-A | Photoelectric conversion device for use in sensing light reflected from medium surface | NEC CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244058-A1 | Galactose Derivative, Drug Carrier and Medicinal Composition | GALK1, GALE, UGGT1 | TSHR 2018/4885SMN1; SMN2 2915/4885POLB 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.