Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 4/20 | 0.33 |
| ▸ | SKP1 | P63208 | 4/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406117 | 0.92 | HSD11B1 (0.37) | HSD11B1AGTR2FFAR4HRH3FFAR1 | |
| SCHEMBL2405635 | 0.92 | PIM2 (0.36) | AGTR2FFAR4FFAR1CKS1BSKP1 | |
| SCHEMBL2405627 | 0.91 | CNR1 (0.38) | HSD11B1FFAR4 | |
| SCHEMBL2411477 | 0.88 | CNR1 (0.40) | — | |
| SCHEMBL2404007 | 0.87 | CPT2 (0.35) | AGTR2FFAR4CKS1BSKP1SKP2 | |
| SCHEMBL2406060 | 0.87 | DKK1 (0.42) | AGTR2FFAR4 | |
| SCHEMBL2408758 | 0.86 | FFAR4 (0.36) | HSD11B1AGTR2FFAR4CKS1BSKP1 | |
| SCHEMBL2411198 | 0.85 | PIM1 (0.36) | AGTR2FFAR4CKS1BSKP1SKP2 | |
| SCHEMBL2405641 | 0.85 | FFAR4 (0.32) | HSD11B1AGTR2FFAR4CKS1BSKP1 | |
| SCHEMBL2405902 | 0.85 | FFAR4 (0.41) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912218-B2 | Alkylthiazol carbamate derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2014-12-16 | — | — | US | disclosed |
| US-20110212963-A1 | ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212963-A1 | ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MET, ALK, REL | HSD11B1 322/4885AGTR2 75/4885FFAR4 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.