Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406193 | 1.00 | AKR1C3 (0.69) | AKR1C3EGFRALDH1A1TBXAS1HTT | |
| SCHEMBL2462983 | 0.91 | AKR1C3 (0.82) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL2462984 | 0.91 | AKR1C3 (0.82) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL3860890 | 0.91 | AKR1C3 (0.58) | AKR1C3EGFRALDH1A1TBXAS1HTT | |
| SCHEMBL2732933 | 0.84 | AKR1C3 (0.72) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL3414243 | 0.84 | AKR1C3 (0.72) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL7764222 | 0.83 | TBXAS1 (0.68) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL7764218 | 0.83 | TBXAS1 (0.68) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL126545 | 0.83 | AKR1C3 (0.69) | AKR1C3ALDH1A1TBXAS1HTTGLA | |
| SCHEMBL83883 | 0.83 | AKR1C3 (0.69) | AKR1C3ALDH1A1TBXAS1HTTALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020132183-A1 | Organic anti-reflective coating material and its preparation | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-09-19 | — | — | US | claimed |
| US-20140155439-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2014-06-05 | — | — | US | disclosed |
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-09-01 | — | — | US | disclosed |
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | ASTELLAS PHARMA INC. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20020132183-A1 | Organic anti-reflective coating material and its preparation | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-09-19 | — | — | US | disclosed |
| US-6368768-B1 | ACRYLATE ESTER COPOLYMER | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-04-09 | — | — | US | disclosed |
| EP-0574519-B1 | POLYMERIC NITRONES HAVING AN ACRYLIC BACKBONE CHAIN | ALLIED SIGNAL INC (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1992015625-A1 | POLYMERIC NITRONES HAVING AN ACRYLIC BACKBONE CHAIN | ALLIED-SIGNAL INC. (US) | 1992-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155439-A1 | ENZYME INHIBITORS | HDAC4, HDAC1, HDAC3 | AKR1C3 401/4885EGFR 1133/4885ALDH1A1 747/4885 |
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | AKR1C3 847/4885EGFR 2597/4885ALDH1A1 1442/4885 |
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | VCAM1, VAPB, VAPA | AKR1C3 2794/4885EGFR 3806/4885ALDH1A1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.