SCHEMBL24068633

SCHEMBL24068633

Cc1ccc(-c2cccc3c2OSNC3)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.33
PDE3B Q13370 3/20 0.31
PDE3A Q14432 3/20 0.31
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24068884 0.90 PDE3B (0.35) PDE3BPDE3A
SCHEMBL24068627 0.86 RIPK1 (0.37) PDE3BPDE3A
SCHEMBL24068659 0.85 PDE3B (0.40) PDE3BPDE3A
SCHEMBL24068632 0.84 SCN9A (0.34) GRM2
SCHEMBL24068846 0.84 S1PR4 (0.33)
SCHEMBL24068786 0.84 CD274 (0.38) KDRGRM2
SCHEMBL24069057 0.80 PRF1 (0.36) PDE3BPDE3A
SCHEMBL24068783 0.79 KDR (0.33) KDR
SCHEMBL24069035 0.76 PRKAB2 (0.38) PDE3BPDE3A
SCHEMBL24069049 0.74 L3MBTL1 (0.33) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021238587-A1 MICROMOLECULAR OXATHIAZINE DERIVATIVE AND USE THEREOF 四川大学华西医院 2021-12-02 WO disclosed