Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24069057 | 0.91 | PRF1 (0.36) | CD274ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL24068754 | 0.86 | CYP1A1 (0.44) | ALDH1A1KDM4ENPC1GAAMAPT | |
| SCHEMBL24068633 | 0.84 | KDR (0.33) | GRM2KDR | |
| SCHEMBL24068627 | 0.83 | RIPK1 (0.37) | — | |
| SCHEMBL24068632 | 0.81 | SCN9A (0.34) | GRM2 | |
| SCHEMBL24068834 | 0.81 | DRD2 (0.44) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24068760 | 0.81 | GSTP1 (0.43) | CD274NPC1RAB9AAURKAKDR | |
| SCHEMBL24068825 | 0.80 | DRD2 (0.43) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL24068884 | 0.80 | PDE3B (0.35) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL24069056 | 0.78 | CD274 (0.42) | CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021238587-A1 | MICROMOLECULAR OXATHIAZINE DERIVATIVE AND USE THEREOF | 四川大学华西医院 | 2021-12-02 | — | — | WO | disclosed |