SCHEMBL24068627

SCHEMBL24068627

Fc1ccc(-c2cccc3c2OSNC3)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.37
PIK3CG P48736 1/20 0.35
PDE4B Q07343 2/20 0.33
PDE4D Q08499 2/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
TDP2 O95551 1/20 0.32
MAPK14 Q16539 4/20 0.32
LRRK2 Q5S007 1/20 0.32
ACKR3 P25106 1/20 0.31
KCNH2 Q12809 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24068632 0.86 SCN9A (0.34)
SCHEMBL24068633 0.86 KDR (0.33) PDE3BPDE3A
SCHEMBL24068786 0.83 CD274 (0.38)
SCHEMBL24068884 0.82 PDE3B (0.35) PDE3BPDE3A
SCHEMBL24068743 0.81 HTR7 (0.35) RIPK1MAPK14LRRK2
SCHEMBL24069057 0.80 PRF1 (0.36) PDE3BPDE3ATDP2
SCHEMBL24068993 0.78 TAAR1 (0.40) PGR
SCHEMBL24069035 0.78 PRKAB2 (0.38) PDE3BPDE3A
SCHEMBL24068820 0.77 HTR1A (0.32)
SCHEMBL24069049 0.76 L3MBTL1 (0.33) PIK3CGPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021238587-A1 MICROMOLECULAR OXATHIAZINE DERIVATIVE AND USE THEREOF 四川大学华西医院 2021-12-02 WO disclosed