SCHEMBL24068754

SCHEMBL24068754

COc1ccc(-c2cccc3c2OSNC3)c(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.44
CYP1B1 Q16678 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2E1 P05181 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP4B1 P13584 1/20 0.44
CYP2B6 P20813 1/20 0.44
CYP3A5 P20815 1/20 0.44
CYP2A7 P20853 1/20 0.44
CYP3A7 P24462 1/20 0.44
CYP2F1 P24903 1/20 0.44
CYP2C18 P33260 1/20 0.44
CYP2C19 P33261 1/20 0.44
CYP2J2 P51589 1/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4F8 P98187 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24068786 0.86 CD274 (0.38) ALDH1A1GAAKDM4ENPC1MAPT
SCHEMBL24068745 0.85 PTGS2 (0.39)
SCHEMBL24068834 0.82 DRD2 (0.44) MAPK1KDM4EKMT2ANPC1TP53
SCHEMBL24068760 0.81 GSTP1 (0.43) CYP3A4CYP1A2CYP2D6CYP2C9CYP2B6
SCHEMBL24068825 0.81 DRD2 (0.43) MAPK1KDM4EKMT2ANPC1MAPT
SCHEMBL24069057 0.80 PRF1 (0.36) CYP2C19ALDH1A1KDM4EHSD17B10MEN1
SCHEMBL24069056 0.79 CD274 (0.42)
SCHEMBL24068849 0.79 L3MBTL1 (0.43) ALDH1A1MAPK1KDM4EHSD17B10MEN1
SCHEMBL24068851 0.78 MAPT (0.37) ALDH1A1KDM4EMEN1KMT2ANPC1
SCHEMBL24068828 0.77 XDH (0.40) PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021238587-A1 MICROMOLECULAR OXATHIAZINE DERIVATIVE AND USE THEREOF 四川大学华西医院 2021-12-02 WO disclosed