SCHEMBL240694

SCHEMBL240694

C=C(C)Cc1cc(C(C)(C)c2cc(CC(=C)C)c(O)c(CC(=C)C)c2)cc(CC(=C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
HIF1A Q16665 3/20 0.42
ALOX12 P18054 2/20 0.42
CYP3A4 P08684 2/20 0.42
HPGD P15428 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2C19 P33261 3/20 0.40
KLF10 Q13118 1/20 0.40
GPR35 Q9HC97 1/20 0.36
CHEK1 O14757 1/20 0.36
DAPK3 O43293 1/20 0.36
RET P07949 1/20 0.36
PDGFRB P09619 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21547611 0.90 ESR1 (0.46) ALOX15MAPK1HTTHIF1AALOX12
SCHEMBL1258536 0.79 KLF10 (0.62) ALOX15MAPK1HTTHIF1AALOX12
SCHEMBL241385 0.79 ALOX15 (0.37) ALOX15MAPK1HTTHIF1AALOX12
SCHEMBL9217050 0.77 AMY1A (0.44) HIF1AALOX12TSHRHSD17B10ALDH1A1
SCHEMBL224429 0.74 ALOX15 (0.61) ALOX15MAPK1HTTHIF1AALOX12
SCHEMBL26134510 0.74 ALOX15 (0.61) ALOX15MAPK1HTTHIF1AALOX12
SCHEMBL948481 0.74 ALOX15 (0.61) ALOX15MAPK1HTTHIF1AALOX12
SCHEMBL31166651 0.73 CYP2D6 (0.59) ALOX15HIF1ACYP3A4HPGDTSHR
SCHEMBL10961301 0.73 ELANE (0.37) ALOX15MAPK1HTTELANE
SCHEMBL19104734 0.73 KLF10 (0.54) ALOX15HIF1AALOX12CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 US disclosed
EP-0517656-B1 Fire-protected polyimide composition CIBA GEIGY AG (CH) 1997-08-20 EP disclosed
EP-0458240-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-27 EP disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0385937-A1 Curable blends based on aromatic bismaleinimides CIBA-GEIGY AG (CH) 1990-09-05 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 EP disclosed
US-4689378-A Stable imide-containing composition from diamino phenyl indane-bis-maleimide and alkenyl phenol CIBA-GEIGY CORPORATION (US) 1987-08-25 US disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP disclosed