SCHEMBL241385

SCHEMBL241385

C=C(C)Cc1cc(C(C)(C)c2cc(CC(=C)C)c(OC)c(CC(=C)C)c2)cc(CC(=C)C)c1OC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
KLF10 Q13118 1/20 0.33
ELANE P08246 1/20 0.33
CYP3A4 P08684 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
CASP1 P29466 1/20 0.31
RECQL P46063 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21547590 0.86 ELANE (0.39) HTTELANECYP3A4ALDH1A1
SCHEMBL21547585 0.84 RXRA (0.35) ALOX15HTTALDH1A1TSHRTDP1
SCHEMBL21547604 0.83 CYP2C19 (0.33) HTTELANECYP3A4
SCHEMBL240694 0.79 ALOX15 (0.53) ALOX15MAPK1HTTKLF10ELANE
SCHEMBL21547557 0.79 MAPT (0.33) ELANE
SCHEMBL10961301 0.79 ELANE (0.37) ALOX15MAPK1HTTELANE
SCHEMBL239741 0.78 ELANE (0.41) HTTKLF10ELANECYP3A4ALDH1A1
SCHEMBL21547581 0.75 RARG (0.32) CYP3A4
SCHEMBL241384 0.74 CYP3A4 (0.46) ALOX15MAPK1HTTCYP3A4ALDH1A1
SCHEMBL21547575 0.74 ACHE (0.35) CYP3A4ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
EP-2417168-A1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS Huntsman Advanced Materials Americas LLC (US) 2012-02-15 EP disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 US disclosed
US-5138000-A High strength molding material CIBA-GEIGY CORPORATION (US) 1992-08-11 US disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0385937-A1 Curable blends based on aromatic bismaleinimides CIBA-GEIGY AG (CH) 1990-09-05 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 EP disclosed
US-4689378-A Stable imide-containing composition from diamino phenyl indane-bis-maleimide and alkenyl phenol CIBA-GEIGY CORPORATION (US) 1987-08-25 US disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP disclosed