Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890339 | 0.95 | THRB (0.58) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13955819 | 0.90 | THRB (0.51) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18123490 | 0.88 | TSHR (0.62) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL22035555 | 0.88 | THRB (0.59) | THRBTSHRACHEMEN1KMT2A | |
| SCHEMBL13872027 | 0.86 | THRB (0.58) | THRBTSHRACHEMEN1KMT2A | |
| SCHEMBL2407776 | 0.86 | THRB (0.58) | THRBTSHRACHEMEN1KMT2A | |
| SCHEMBL26582579 | 0.85 | THRB (0.57) | THRBTSHRACHE | |
| SCHEMBL14904497 | 0.84 | THRB (0.70) | THRBTSHRACHEMEN1KMT2A | |
| SCHEMBL29700318 | 0.84 | THRB (0.56) | THRBTSHRACHE | |
| SCHEMBL13309598 | 0.83 | THRB (0.64) | THRBTSHRACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | MITSUI CHEMICALS, INC. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | MITSUI CHEMICALS, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | PAM, CAD, FHIT | THRB 873/4885TSHR 2948/4885CHRNB2 2841/4885 |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | HRH3, HRH1, HRH2 | THRB 639/4885TSHR 861/4885CHRNB2 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.