Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409996 | 0.93 | HTR6 (0.33) | PLCG1KAT8HTR6KAT6AKAT5 | |
| SCHEMBL2411042 | 0.90 | HTR6 (0.33) | KAT8HTR6KAT6AKAT5 | |
| SCHEMBL2409873 | 0.90 | HTR6 (0.34) | PLCG1KAT8HTR6KAT6AKAT5 | |
| SCHEMBL2411862 | 0.89 | RORC (0.36) | PLCG1KAT8HTR6KAT6AKAT5 | |
| SCHEMBL4998756 | 0.89 | HTR6 (0.34) | KAT8HTR6KAT5 | |
| SCHEMBL2410573 | 0.88 | GPBAR1 (0.34) | KAT8HTR6KAT6AKAT5 | |
| SCHEMBL2409898 | 0.88 | MET (0.38) | PLCG1KAT8HTR6KAT6AKAT5 | |
| SCHEMBL2408643 | 0.88 | SOS1 (0.33) | KAT8HTR6 | |
| SCHEMBL2408012 | 0.84 | PTGDR2 (0.31) | PLCG1HTR6 | |
| SCHEMBL2410115 | 0.83 | RORC (0.38) | KAT8HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |