Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242059 | 0.69 | NPSR1 (0.31) | MTNR1A | |
| SCHEMBL242056 | 0.66 | TOP1 (0.37) | — | |
| SCHEMBL5440135 | 0.64 | NR4A1 (0.41) | — | |
| SCHEMBL30800730 | 0.58 | GPR84 (0.41) | — | |
| SCHEMBL19960410 | 0.57 | ALDH1A1 (0.48) | — | |
| SCHEMBL28347371 | 0.56 | CYP1A2 (0.50) | — | |
| SCHEMBL3180469 | 0.56 | ATM (0.33) | — | |
| SCHEMBL1667 | 0.56 | ALDH1A1 (0.35) | — | |
| SCHEMBL13583073 | 0.56 | ALDH1A1 (0.35) | — | |
| SCHEMBL1025256 | 0.56 | KDM1A (0.43) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076524-B1 | CHIRAL PHOSPHORUS COMPOUND | JOHNSON MATTHEY PLC (GB) | 2016-04-20 | — | — | EP | disclosed |
| US-8735583-B2 | Chiral phosphorus compound | JOHNSON MATTHEY PUBLIC LIMITED CO. (GB) | 2014-05-27 | — | — | US | disclosed |
| US-20130150583-A1 | CHIRAL PHOSPHORUS COMPOUND | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-06-13 | — | — | US | disclosed |
| US-8404843-B2 | Chiral phosphorus compound | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-03-26 | — | — | US | disclosed |
| US-20120264940-A1 | CHIRAL PHOSPHORUS COMPOUND | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-10-18 | — | — | US | disclosed |
| US-8222415-B2 | Chiral phosphorus compound | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-07-17 | — | — | US | disclosed |
| US-20120004411-A9 | CHIRAL PHOSPHORUS COMPOUND | JOHNSON MATTHEY PLC (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20100240898-A1 | CHIRAL PHOSPHORUS COMPOUND | JOHNSON MATTHEY PLC (GB) | 2010-09-23 | — | — | US | disclosed |
| EP-2076524-A1 | CHIRAL PHOSPHORUS COMPOUND | Johnson Matthey Public Limited Company (GB) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008041029-A1 | CHIRAL PHOSPHORUS COMPOUND | JOHNSON MATTHEY PLC (GB) | 2008-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264940-A1 | CHIRAL PHOSPHORUS COMPOUND | PIK3CA, RECQL, P2RY1 | MTNR1A 2917/4885 |
| US-20120004411-A9 | CHIRAL PHOSPHORUS COMPOUND | PIK3CA, RECQL, P2RY1 | MTNR1A 2917/4885 |
| US-20100240898-A1 | CHIRAL PHOSPHORUS COMPOUND | PIK3CA, RECQL, P2RY1 | MTNR1A 2917/4885 |
| US-20130150583-A1 | CHIRAL PHOSPHORUS COMPOUND | ALPP, PTH1R, CALCR | MTNR1A 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.